Khorfakkan came from a 1-3 down to fight back and secured a 4-3 dramatic win over ten-man Al Wasl at Zabeel Stadium on Saturday.
Al Wasl started the game fiercely, and they needed just 15 minutes to find the breakthrough, with Aléxis Pérez powering a superb first-time volley into the bottom corner.
The visitors responded in quick form to level the scores thanks to Oumar Keita's powerful header that kept Khaled Alsenaani watching the ball, hitting the net four minutes after Al Wasl's opener.
Nicolas Gimene put Al Wasl ahead again in the 22nd minute when Fabio Lima cut inside from the right flank, squaring the ball to Gimene, who powered a first-time effort into the back of the net.
The hosts' pressure to cement their lead paid off in the 37th minute when Khorfakkan's defender Abdalla Elrefaey inadvertently turned Aléxis Pérez's cross into his net.
Malek Janeer received a straight red card after the referee consulted the VAR due to a bad foul on Cheickna Doumbia, and that decision was the turning point of Zabeel's game.
The visitors made use of Al Wasl's red card, turned the screw, and claimed their rewards when Pedro Pavlov launched a brilliant first-time volley that smashed the back of the net.
Khorfakkan turned the game around seven minutes after the hour-mark when Mattheus De Andrade poked the rebound in to make it 3-3.
The comeback was completed for the visitors and they turned the game into its head eight minutes from the time as Mattheus De Andrade turned from scorer to a provider after squaring the ball to Saeed Ahmed Abdulla, who scored a low, first-time shot from the six-yard box.
The win means Al Wasl are 9th with seven points, while Khorfakkan sit 10th with six points.