Al Nasr's perfect start under Alfred Schreuder in the ADNOC Pro League ended as Al Wasl battled back to be the Bur Dubai Derby's winner with a 2-1 victory at Zabeel Stadium on Saturday.
The result left Al Nasr third with six points, while Al Wasl jumped to the second spot with seven points.
It took 22 minutes for Al Nasr to break the deadlock when Adel Taarabt capitalized on a defensive mix-up and drove a shot from a tight angle.
Al Wasl dominated the game after Al Nasr's opener, but their players forgot their scoring boots at home during the first half.
Fabio Lima was unlucky as his brilliant sublime strike from the edge of the penalty box five minutes before the break smashed the post.
Lima continued his brilliant effort to restore the parity for his side before going to the dressing room for the break, as his powerful low effort from a free-kick was parried out by August's best goalkeeper Abdulla Altamimi.
The hosts heaped their pressure to bring the level and got what they wanted eight minutes after the break when Caio Canedo picked up the ball inside the box, rounded a defender, and lashed it past goalkeeper Abdulla Altamimi.
Five minutes after the hour-mark, Fabio Lima hit the post again with an excellent side-footed effort.
The comeback was completed in the 74th minute when Ali Saleh hooked a first-time volley into the top corner of the net.
Ali Saleh nutmegged a defender, hitting the ball through his legs, to get into the box, and his low cross was met by a clinical finish from Soufiane Bouftini to secure the three points for the ADNOC Pro League's title holders in the 82nd minute.